Abstract
Clinical evaluation should be consulted in order to determine whether an overdose or not, due to the lack of safety data on the characteristics of the use of the drug in clinically significant or certain groups of patients.
Cover Letter
Introduction
Spontaneous use of some drugscan provoke new diseases. A Risk-based approach is an approach that uses methods for identifying risk areas. When prescribing the drug, many factors should be taken into account: indications for its use, contraindications, special indications and precautions, interaction with other medicinal substances, use during pregnancy and lactation, effect on the ability to drive vehicles and potentially dangerous mechanisms, and toxicity. Most” ulcerogenic " drugs cause not chronic, but acute ulcers on the gastroduodenal mucous membrane, and in connection with this, the drug is stopped. Acetylsalicylic acid, indomethacin, butadione, reserpine and many other pharmacological drugs belong to the “ulserogenic” active substances. Clinical Control confirms that the indicated prearates provoke an exacerbation of ulcer disease. Based on what has been said, the intake of acetylsalicylic acid, indomethocine, reserpine and other substances of ulcerogenic action in the indicated diseases is contraindicated.
90% of most acute hepatitis are caused by viruses, alcohol and drugs. The cholestatic form of medicinal hepatitis is often caused by aminazine and its derivatives, phosphoestrol, aymaline, etc. it occurs thanks to the intake of preparations. In most patients taking hepatotoxic drugs, serum control of aminotransferase, QQTF, alkaline phosphatase and bilirubin is required no later than 14 times in 1 day due to the development of drug hepatitis in a less symptomatic form. At present, more than 1000 drug compounds with hepatotoxic potential are known. The vast majority of diuretics activate the excretion of sodium with urine. A low concentration of sodium in plasma is characteristic of some kidney diseases. Hyponatremia is also characteristic of heart failure stagnation. Hyponatremia is also observed in pathologies of the gastrointestinal tract. Hypermagnesimia. The above-mentioned hypermagnesemia is accompanied by renal failure. Hypermagnesemia is also noted in hypothyroidism, hepatitis, malignant tumors. In such a situation, treatment doctors must necessarily control the dynamics of changes in the course of treatment, orienting themselves with the results of laboratory indicators.
Harmful effects of antibiotics.
Negatively affects kidney and liver function; puts pressure on bone marrow and immunity; fungus may occur; after a common cough, they may grow up and become sinusitis; children's growth time is hampered; antibiotic-related bloody diarrhea, skin eczema, digestive problems may occur. With intensive and inappropriate use of antibiotics, resistant microorganisms are formed. As a result, 2-3 months later, severe anemia is experienced due to a decrease in blood cells in the bone marrow.
Toxicity.
To treat anemia, iron is usually prescribed 30-60 mg every day. At such a dose, there may sometimes be pain in the abdomen, nausea, vomiting.
Iron is a strong oxidant, and an excess of its dosage can lead to dire consequences. For example: to chronic inflammation of the liver, increased risk of liver malignancy, as well as ischemic heart disease. By measuring the check transfer of gemochromotosis, we determine the pathology before clinical signs of iron excess appear. The copper preparation is usually well tolerated and the dose is 5 mg per day without fear for adults. If the dose is > 7 days, it causes abdominal pain, nausea, vomiting and diarrhea. Higher doses cause liver damage. Iodine-containing preparations iodine >2 mg too much can disrupt the hormone secretion of the thyroid gland. In people with prolonged iodine deficiency or goiter, acute excess use of iodine can lead to hyperthyroidism and, to a lesser extent, thyrotoxicosis. Selenium preparations. Taking 500 mg of selenium every day is safe for adults. Prolonged use of >900 mg can cause nausea, vomiting, hair loss, changes in The Shape of nails, fatigue, and peripheral neuropathies.Zinc is considered a non-toxic microelement at a daily dose of <100mg. When the dose is >150, zink can cause nausea, vomiting and impaired copper absorption. In very large doses (>300 mg per day), a violation of the function of the immune system and an increase in the level of high-density cholesterol in the blood may occur. Uix, atherosclerosis, primary osteosarcoma may be present in zinc overdose.
The result.
The effect of treating people depends on how much the basic principles of farmocotherapy are followed. When prescribing pharmacological drugs, an individual approach is important.
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Keywords
References
Literature
1. K.M.Hasanova. Replacement therapy with micronutrients in older people. Baku, 2016.
2. D.F.Chebotarev. Kiev, 1977.
3. B.A.Tkarika. Клиническая Биохимия. Moscow, 2004.
Article Info:
Publication history
Published: 25.Feb.2025
Copyright
© 2022-2025 Azerbaijan İnternal Medicine Society. Published by "Uptodate In Medicine" health sciences publishing. All rights reserved.Related Articles
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